Search results for "Glucose‐dependent insulinotropic polypeptide"

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Is the Secret in the Gut? SuperJump Activity Improves Bone Remodeling and Glucose Homeostasis by GLP-1 and GIP Peptides in Eumenorrheic Women

2022

We showed that twenty weeks of SuperJump activity, an innovative workout training performed on an elastic minitrampoline, reduced bone resorption and increased bone formation in eumenorrheic women acting on the key points of the regulation of bone metabolism. The present study analyzed whether the gastrointestinal hormones are involved in the mechanism of action and if it has an impact on glucose homeostasis. The control group was composed of twelve women, similar to the exercise group that performed SuperJump activity for twenty weeks. The analysis was performed on blood samples and investigated GLP-1, GIP, GLP-2, PYY, ghrelin, glucose, insulin, insulin resistance, β-cell function, and ins…

Glucagon-like peptide-1endocrine systemBiological mechanismsGeneral Immunology and MicrobiologyGlucose‐dependent insulinotropic polypeptidedigestive oral and skin physiologyPhysical healthbiological mechanisms; physical health; sports and exercise physiology; glucagon-like peptide-1; glucose-dependent insulinotropic polypeptideGeneral Agricultural and Biological Scienceshormones hormone substitutes and hormone antagonistsGeneral Biochemistry Genetics and Molecular BiologySports and exercise physiology
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Phenotyping of type 2 diabetes mellitus at onset on the basis of fasting incretin tone: Results of a two-step cluster analysis.

2015

Aims/Introduction According to some authors, in type 2 diabetes there is a reduced postprandial action of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). However, little is known about the role of fasting incretins in glucose homeostasis. Our aim was to evaluate, through a two-step cluster analysis, the possibility of phenotyping patients with type 2 diabetes at onset on the basis of fasting GLP-1, GIP and ghrelin. Materials and Methods A total of 96 patients with type 2 diabetes within 6 months of onset (mean age 62.40 ± 6.36 years) were cross-sectionally studied. Clinical, anthropometric and metabolic parameters were evaluated. At fasting the follow…

Blood GlucoseMalemedicine.medical_treatmentEndocrinology Diabetes and MetabolismSettore MED/13 - Endocrinologiachemistry.chemical_compound0302 clinical medicineGlucagon-Like Peptide 1Glucose homeostasisCluster AnalysisHomeostasis030212 general & internal medicineGeneral MedicineArticlesMiddle AgedGlucagon-like peptide-1GhrelinGlucagon‐like peptide‐1PhenotypeClinical Science and CareFemaleOriginal Articlehormones hormone substitutes and hormone antagonistsGlucagon-like peptide-1medicine.medical_specialtyGlucose-dependent insulinotropic polypeptideIncretin030209 endocrinology & metabolismGastric Inhibitory PolypeptideGhrelin; Glucagon-like peptide-1; Glucose-dependent insulinotropic polypeptide; Endocrinology Diabetes and Metabolism; Internal MedicineIncretins03 medical and health sciencesInsulin resistanceGlucose‐dependent insulinotropic polypeptideInternal medicineDiabetes mellitusmedicineInternal MedicineHumansAgedAdiponectinbusiness.industryInsulinmedicine.diseaseEndocrinologyGlucosechemistryDiabetes Mellitus Type 2Glycated hemoglobinInsulin ResistancebusinessJournal of diabetes investigation
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